Too many platelets in the Spleen
The spleen, which is part of the lymphatic system, is responsible for storing bodily fluids. The spleen has multiple functions in the body. It recycles red blood cells, stores platelets and also helps to store them. In most cases, a third of platelets are stored within the spleen. The spleen will expand and store more platelets, causing a decrease in platelet circulation in the blood. This will result in low platelet counts in the bloodstream, which can lead to thrombocytopenia. A spleen that is enlarged can lead to liver disease such as cirrhosis. The liver becomes damaged and does not function properly. A swollen spleen can be caused by myelofibrosis. Myelofibrosis is characterized by a scarred bone marrow that does not produce enough red blood cells.