Thrombotic Thombocytopenic Purpura
This is a rare disorder of the blood. This condition can lead to blood clots that block blood flow. The brain, kidneys, and heart can suffer serious complications when oxygenated blood supply is restricted and cannot reach them properly. These small clots destroy platelets throughout the body. Platelets are used up and fewer remain in the blood. This can lead to bleeding. TTP is caused by a deficiency in a blood enzyme that prevents platelet clumping, which leads to blood clots. Minor deficiency is harmless, but a severe deficiency may lead to blood clots forming in the vessels. This enzyme deficiency is either inherited or acquired. It can be caused by autoantibody or gene mutation. If it is acquired disease, the gene may not be the cause. Instead, the body produces antibodies that block enzyme activity, resulting in blood clots. TTP is more likely to occur when certain health conditions, such as pregnancy or surgery, increase the risk for blood clotting. In TTP, internal bleeding is the cause of the tiny, red, and purple spots that appear on the skin. These spots, also called petechiae and which look like a rash, are known as TTP. TTP may cause permanent damage to the brain if it is affected. TPP is not treatable immediately and can last from days to several months.
