Epinephrine
Epinephrine is the preferred treatment for anaphylactic emergencies. It is a life-saving drug because its mechanism of action fundamentally opposes that of the anaphylactic mediators. However, prompt administration with correct route adoption is also essential. It is now well-established that reluctance or delay in administering epinephrine correlates substantially with the fatality rate of anaphylaxis.
The optimal route of administration is the upper outer region of the quadriceps muscle. The optimal time interval is 5 to 15 minutes, but it may be shortened in the event of a severe anaphylactic reaction. If the initial dose does not substantially alleviate symptoms, the physician may administer an additional dose or intravenous epinephrine.
The adverse effects of epinephrine do not in any way diminish its effectiveness.
The autoinjector is a highly efficacious method of administration. This makes administration simple for even non-professionals. It is even possible to inject it through apparel. In cases of previous anaphylactic attacks, the physician may prescribe an epinephrine auto-injector.
