Taking Diuretics
Diuretics may increase the risk of developing gout by increasing the accumulation of uric acid crystals in a joint or adjacent tissue. The reason for this is that diuretics increase urination, reducing the quantity of fluids in the body. The remaining fluid, however, has a higher concentration, which may increase the risk of developing urate crystals that cause gout. Certain diuretics can also inhibit the kidneys’ capacity to eliminate urate, a component of uric acid. The physician will determine whether or not you should continue taking diuretics or transition to another medication. There are a number of additional blood pressure-lowering medications that also reduce uric acid levels.