Pollution
Atopic dermatitis and pollution as its cause have been discussed for a long time, but only recently have ayl-hydrocarbon receptors and their role in triggering itchy starch responses been investigated. The environment is home to numerous gases and pollutants, and these pollutants are responsible for the onset of numerous illnesses, including asthma and multiple skin infections. Recent research indicates that numerous air contaminants and environmental compounds are toxic and hazardous. Tobacco smoke, volatile organic compounds, nitrogen oxide, toluene, and formaldehyde have been identified as risk factors for the development of atopic dermatitis. These compounds induce oxidative stress, which can have a negative effect on the epidermis or lead to immune dysregulation. These pollutants can activate the transcription factor AhR (aryl hydrocarbon receptors) in addition to oxidative stress. This AhR transcription factor has been shown to target a gene responsible for epidermal innervation and inflammation. To comprehend how environmental pollution contributes to the onset of atopic dermatitis, additional research is required; however, the studies that have been performed and conducted thus far strongly suggest a correlation between pollution and the onset of atopic dermatitis. To prevent and treat atopic dermatitis, more comprehension, improved knowledge, and a more effective strategy are necessary.
