Causes Of Atopic Dermatitis
The fact that eczema is a chronic inflammatory skin disease with a high prevalence, particularly among children, raises health concerns. Pervasiveness is influenced by a variety of factors, including genetic predisposition, immunity issues, and environmental factors. It is crucial to identify the disease’s causes and contributing factors so that they can be controlled. In the case of atopic dermatitis, additional measures to limit exposure to certain stimuli are required. Although the original causes of atopic dermatitis are not completely understood, it is believed that a combination of genetic factors and abnormal immune responses to environmental conditions can induce the condition.
Immunological system
Immunological diseases involve the individual’s immune system. The human immune system is responsible for protecting the body against all types of extraneous particles, including microorganisms and other external particles, making it a highly sophisticated and sensitive system. Atopic dermatitis is not merely an inflammation of the skin, but a disease induced by an overactive immune system. While rashes and redness are visible on the surface of the skin, the true problem lies within. The allergens and irritants cause rashes on the skin, and scratching the skin aggravates the condition. The human epidermis consists of three layers. As the outermost layer, the epidermis is responsible for preventing extraneous substances, such as viruses, bacteria, and infections, from entering the body, thereby preserving its internal safety and health. This layer becomes more sensitive and fragile when a person has atopic dermatitis, making it susceptible to inflammation induced by the immune system. Scratching the skin damages skin cells further, making it easier for extraneous substances to penetrate the skin. When this substance breaches the skin’s protective barrier, the body’s immune cells become active and begin destroying the invading particles by activating the defender. The discharge of these substances by the defence cells results in a ruddier and itchier skin surface. Normally, the substance disappears after a period of time, but in atopic dermatitis, these cells remain active and continue the inflammatory process, and skin continues to react, resulting in underlying inflammation and starch deposition on the skin. The itching cycle persists, and the skin condition worsens.
