Inflammation
In severe cases of atopic dermatitis, inflammation begins to develop. When a person has atopic dermatitis, the outermost layer of skin becomes more sensitive and fragile, making it prone to inflammation. Scratching the skin damages skin cells further, making it easier for extraneous substances to penetrate the skin. When this substance breaches the skin’s protective barrier, the body’s immune cells become active and begin destroying the invading particles by activating the defender. The discharge of these substances by the defence cells results in a ruddier and itchier skin surface. The substance typically disappears over time. Nonetheless, in atopic dermatitis, these cells remain active and continue the inflammatory process, causing the skin to continue to react and cause underlying inflammation.
